Get Your Cell Number Right When Monitoring Immune Cell Populations

Immune monitoring requires an accurate count

Cell enumeration by flow cytometry is an established method in both research and clinical settings. It has widespread clinical applications, from monitoring disease progression to assessing the therapeutic efficacy of drugs. In the case of immunotherapies, the absolute count of specific PBMC sub-populations is often a key requirement during clinical development.

Caprion provides a quality service that delivers reproducible enumeration of cells while following strict quality standards.

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cell counts

Leveraging our deep expertise in multiparametric flow cytometry, Caprion delivers sensitive and precise cell enumeration while reducing sample processing time, allowing for a cost- and time-efficient assay. Using TrucountTM tubes or Flow-CountTM fluorospheres, we can provide cellular counts for exploratory, secondary, or primary endpoints – depending on the requirement of your study. In addition to cell enumeration, our state-of-the-art instrumentation allows us to simultaneously monitor for cell behaviour and surface expression changes.

Applications:

  • CD34+ cells: enumeration in whole blood after mobilization using hematopoietic growth factors and following guidelines set by the ISHAGE (International Society of Hematotherapy and Graft Engineering)
  • Validated TBNK – CD4/CD8 T cells, CD19 B cells, CD16/CD56 NK: monitoring in different clinical settings
  • Residual leukocytes: enumeration for quality control of leukoreduced blood products
  • Immunotherapies: enumeration of myeloid-derived suppressor cells (MDSC) and CAR T cells