Caprion

Accelerating precision medicine™

ProteoCarta Technology Overview

Successful proteomic studies require careful study design, sample preparation, study execution, and data analysis to identify biologically and clinically relevant proteins. Caprion has over a decade of experience collaborating with pharmaceutical, biotech, and non-for-profit organizations to design and execute proteomics studies to meet customer needs by combining our expertise in three key areas:

 

Sample Preparation

Fractionation or enrichment improves assay sensitivity and maximizes the opportunities to discover novel, biologically-relevant biomarkers. Strategies routinely utilized at Caprion include:

  • Depletion of high abundance proteins
  • Chromatographic fractionation
  • Subcellular fractionation
  • Enrichment of membrane proteins, secretory proteins, or phosphoproteins
  • Isolation of exosomes or specific organelles

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Mass Spectrometry

Multiple MS technologies to support both unbiased and targeted proteomics studies for discovery through to assay deployment for regulated environments

  • LC-MS/MS for unbiased discovery of novel biomarkers and drug targets
  • MRM mass spectrometry for biomarker screening, verification, and fit-for-purpose assays
  • Robust processes for high quality, reproducible results
  • Can be adapted for analysis of specific post-translational modifications

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Bioinformatics and Biostatistics

Caprion’s multidisciplinary bioinformatics team is an integral part of every project, from study design and quality control through to statistical analysis and biological interpretation of results. Caprion’s PhD-level bioinformatics team has experience with:

  • Optimization of study design to avoid common pitfalls
  • Identification of outliers and pre-analytical biases
  • Selection of statistical tests to match the study design and goals
  • Extensive data interpretation, including pathway analysis and literature assessment

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Caprion

Accreditations & Certifications

CAP accreditation and CLIA certification

CAP Accredited

Headquarters

+1 514.360.3600
+1 877.776.3443
141 President Kennedy Ave., Suite SB-5658
Montreal, Quebec
CANADA

USA

Primity Bio
48383 Fremont Blvd
Suite 118
Fremont, CA 94538
Tel.: +1 858.229.2529

Serametrix
2235 Farraday Ave,Suite N,
Carlsbad, CA, 92008, USA
Tel: +1 760 652 4060

HistoGeneX
1331 W 75th St #401,
Naperville, IL 60540, USA
Tel: +1 630-473-6655
info@histogenex.com

AUSTRALIA

Serametrix Party Limited
Suite 4/54-60 Briggs Street
Camperdown, NSW, 2050
Australia
+61 2 9168 5908

EUROPE

Caprion Biosciences Inc.
+32 (0) 71 96 23 36
8 rue Adrienne Bolland
6041 Gosselies
BELGIUM

Serametrix
Unit 22, Surrey Technology Centre,
40 Occam Road,
Guildford, Surrey, UK
GU2 7YG
Tel: +44 1483 685599

Antwerp, Belgium
HistoGeneX
Sint-Bavostraat 78
2610 Antwerpen (Wilrijk)
Belgium
Tel: +32 3 50 20 500
Sample Reception: +32 3 50 20 620
Shipments: +32 3 50 20 625

CANADA LAB

201 President Kennedy Ave., Suite PK-3900
Montreal, Quebec
CANADA
+1 514.360.3600
+1 877.776.3443



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Contact

+1 877.776.3443

info@caprion.com