Caprion

Accelerating precision medicine™

Fit-for-purpose Assays

Caprion uses Multiple Reaction Monitoring (MRM) mass spectrometry to develop robust, quantitative assays for non-clinical and clinical use. Fit-for-purpose assay development often follows a biomarker discovery study, but can also be applied to proteins of interest from other sources. Because the fit-for-purpose approach includes assay qualification and/or validation, it is usually applied once the number of proteins of interest have been narrowed from 100s to 10s. MRM assays are typically antibody-free, can be rapidly and easily multiplexed, and provide high specificity and sensitivity. For low abundance targets, antibody enrichment can also be combined with MRM to further enhance assay sensitivity. Our experienced team uses a tiered approach to develop fit-for-purposes assays that meet customer and regulatory requirements.

Applications

Qualification and validation of biomarker assays for use as primary/secondary endpoints or as exploratory markers in regulated environments

  • Pharmacodynamics
  • Monitoring of drug efficacy and response
  • Patient selection and stratification
  • Surrogate endpoints
  • Diagnosis and disease monitoring

Benefits of Caprion’s Fit-for-Purpose Assays

Multiplexed, antibody-free assays can be rapidly developed for biomarker verification, validation, and application in support of non-clinical and clinical studies

  • Customized biomarker assays to meet evolving requirements throughout the drug development lifecycle
  • Highly specific, sensitive mass-spectrometry based assays
  • Absolute quantitation
  • GLP capability with QA environment

 


Caprion

Accreditations & Certifications

CAP accreditation and CLIA certification

CAP Accredited

Headquarters

+1 514.360.3600
+1 877.776.3443
141 President Kennedy Ave., Suite SB-5658
Montreal, Quebec
CANADA

USA

Primity Bio
48383 Fremont Blvd
Suite 118
Fremont, CA 94538
Tel.: +1 858.229.2529

Serametrix
2235 Farraday Ave,Suite N,
Carlsbad, CA, 92008, USA
Tel: +1 760 652 4060

HistoGeneX
1331 W 75th St #401,
Naperville, IL 60540, USA
Tel: +1 630-473-6655
info@histogenex.com

AUSTRALIA

Serametrix Party Limited
Suite 4/54-60 Briggs Street
Camperdown, NSW, 2050
Australia
+61 2 9168 5908

EUROPE

Caprion Biosciences Inc.
+32 (0) 71 96 23 36
8 rue Adrienne Bolland
6041 Gosselies
BELGIUM

Serametrix
Unit 22, Surrey Technology Centre,
40 Occam Road,
Guildford, Surrey, UK
GU2 7YG
Tel: +44 1483 685599

Antwerp, Belgium
HistoGeneX
Sint-Bavostraat 78
2610 Antwerpen (Wilrijk)
Belgium
Tel: +32 3 50 20 500
Sample Reception: +32 3 50 20 620
Shipments: +32 3 50 20 625

CANADA LAB

201 President Kennedy Ave., Suite PK-3900
Montreal, Quebec
CANADA
+1 514.360.3600
+1 877.776.3443



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Contact

+1 877.776.3443

info@caprion.com