Caprion

Accelerating precision medicine™

Posters and White Papers

Proteomics/Mass Spectrometry

Caprion - Poster - SITC - Succesful Monitoring of Checkpoint Inhibitors by Flow Cytometry SITC 2018

Mass Spectrometry Platforms for High Coverage Process-Specific Host Cell Protein Identification and Quantitation AAPS 2018

Absolute Quantitation of Biotherapeutic Drug Product and Endogenous Protein in Human Serum Using a Hybrid Immunoassay-LC/MS Approach AAPS 2018

Absolute Quantitation of 5 Antibody Drug Products in Dosed Monkey Serum, CSF and Brain Lysate for Lead Candidate Identification Using LC-MRM/MS AAPS 2018

Measurement of Protein X by LC-MRM/MS Using the AQUA Approach in Dissected FFPE Breast and Gastric Tumor Tissue AAPS 2018

Fit-for-Purpose Validation for the Measurement of 29 Cytokines in Human Plasma by MesoScale AAPS 2018

An LC-MRM/MS-Based PD Assay for Monitoring Site Occupancy of an Oncogene Protein in Tumor Xenograft Tissue from Mice Dosed with Alkylating Agent AAPS 2018

Metaproteomic Analysis of the Infant Fecal Microbiome HUPO 2018

Protein Biomarkers Predictive of Multivalent Response to a Novel Dengue Vaccine European Congress of Immunology 2018

Mass Spectrometry Platforms for High Coverage Process-Specific HCP Identification and Quantitation Bioprocessing Summit 2018

Metaproteomic analysis of the infant fecal microbiome , Translational Microbiome, May 2018

Acute febrile illness surveillance in a malaria endemic region of Madagascar: biomarker discovery for differentiation of bacterial and viral illnesses, ECCMID 2018

Use of Mass Spectrometry for High Coverage Process Specific HCP Identification and Quantitation , BEBPA 2018

High Coverage Process Specific HCP Identification and Quantification Using Mass Spectrometry, Peptalk 2018

Identification of Huntington’s Progression and Disease Biomarkers Using Mass Spectrometry, NINDS/NIH Workshop 2017

Multiplexed Mass Spectrometry Assay Identifies Neurodegeneration Biomarkers in CSF, CNS Summit, Florida, 2017

High Coverage Process Specific HCP Identification and Quantification Using Mass Spectrometry - Update, 3rd BIOLOGICS AND BIOSIMILARS CONGRESS, 2017

High Coverage Process Specific HCP Identification and Quantification Using Mass Spectrometry BIOLOGICS MANUFACTURING ASIA, 2017

Sigma-2/PGRMC1 antagonist pharmacodynamic target engagement biomarker discovery for Alzheimer's disease, 2016

Metaproteomic analysis of the infant fecal microbiome TARGETING THE MICROBIOME, 2016

From Discovery to the Clinic: Development of a Mass Spectrometry-based Test for Differentiation of Benign vs. Malignant Lung Nodules BIOMARKER WORLD CONGRESS, 2015

Investigating the proteome and phosphoproteome of renal cell carcinoma and the effect of delayed times to tissue fixation for FFPE and frozen samples AACR, 2015

Biomarker Discovery in Cerebrospinal Fluid for Schizophrenia and Antipsychotic Drug Treatment-Induced Weight Gain ASMS, 2014

Proteomics Study on the Effect of General Anesthesia on Human Plasma and Peripheral Blood Mononuclear Cells ASMS, 2014

Impact of Human Blood Specimen Collection Processing, and Storage on Protein Integrity and Implications for Use in Clinical Research ASMS, 2014

Development of a Mass Spectrometry Based Pharmacokinetic (PK) Assay for the Measurement of RLIP76 Protein and Proteoliposome in Human Serum AAPS, 2014

Impact of Human Blood Specimen Collection, Manipulation, and Storage on Protein Integrity and Implications for Use in Clinical Research HUPO, 2013

Evaluation of a Multiplexed Mass Spectrometry-Based Method for Measuring Candidate Peptide Biomarkers in Alzheimer’s Disease Neuroimaging Initiative (ADNI) CSF ASMS, 2013

A Highly Multiplexed MRM-based Screening Assay for Preclinical Nephrotoxicity Studies SOT, 2013

Immune Monitoring

Patient-specific Fluorescence Aberration Profiles during Longitudinal Clinical Trials AAPS 2018

Characterization of two kinase-modulating compounds in tumor infiltrating lymphocytes (TILs) using flow cytometry and Meso Scale Discovery AAPS 2018

Fit-For-Purpose GLP Validation of an Intra-Cellular Cytokine Staining Assay - AAPS 2018 AAPS 2018

PD-1-positive population in resting T cells identified using a qualified flow cytometric method - AAPS 2018 AAPS 2018

Patient-specific Fluorescence Aberration Profiles During Longitudinal Clinical Trials ICCS 2018

Flow Cytometry Assay Validation as a Biomarker Versus in a Drug Development Setting ICCS 2018

Characterization of Two Potential Immunotherapeutics in Tumor Infiltrating Lymphocytes (TILs) Using Flow Cytometry and Meso Scale Discovery, ASCO 2018

Fit-For-Purpose GLP Validation of an Intra-Cellular Cytokine Staining Assay , CYTO, 2018

Case Studies: Atypical, Patient-Specific Profiles Observed During Longitudinal Clinical Trials, CYTO, 2018

Lab Hacks: Inspiring Innovation in Cytometry Through Open , CYTO, 2018

PD-1-positive population in resting T cells identified using a qualified flow cytometric method, Keystone Combinations, 2018

Fit-For-Purpose GLP Validation of an Intra-Cellular Cytokine Staining Assay, ICI Boston, 2018

Extension of whole blood sample stability for flow cytometry analysis through the use of specialized blood collection tubes, European Bioanalysis Forum (EBF) Barcelona, 2017

Development of an Absolute Quantitation Assay for Simultaneous Measurement of 9 Proteins From Cell Lysates by MRM IMMUNE PROFILING WORLD VACCINE, 2016

Direct Identification of Neo-Epitopes in Tumor Tissue CANCER IMMUNOTHERAPY, 2016

Stability Assessment of Various Flow Cytometry Markers in Stabilized Whole Blood CYTO, 2016

Analysis of Protein Phosphorylation Using Multiparametric Flow Cytometry (White Paper)

Immune Profiling of Patients Vaccinated with DPX-Survivac Demonstrates Durable Polyfunctional CD4+ and CD8+ Cells in Ovarian Cancer Patients AACR, 2014

High Dimensional Flow Cytometry for Comprehensive Immune Monitoring of Vaccine Clinical Trials FOCI, 2012

High Dimensional Flow Cytometry for Comprehensive Immune Monitoring in Clinical Trials CCA, 2011